ION’s assay platforms are scientifically validated to deliver high sensitivity, robust screening windows, and reliable data across a range of ion channel and transporter targets.
Detects subtle changes with strong signal amplitudes.
Extensively validated with strong correlation to reference methods.
Consistent performance across experiments and laboratories.
Wide dynamic range for reliable hit detection and characterization.
Brilliant Calcium produces larger responses than Calcium 5 in a Gq GPCR assay.
Data provided by UF Scripps.
Brilliant Calcium beats ThermoFisher’s Fluo-4 NW kit in a muscarinic receptor assay.
Brilliant Thallium outperforms Molecular Devices Potassium Channel Assay in a head-to-head.
Data provided by UF Scripps.
50% larger response yields larger Z’ – enabling you to identify hits with more confidence
Data source: Top 10 Pharmaceutical Company.
ION’s thallium-free potassium channel assays measure potassium flux, providing a safer formulation with equally robust screening windows.
Sodium-dependent SLC Transporter Assays can measure the activity of electroneutral transporters, unlike membrane potential assays.
Sodium-dependent SLC Transporter Assays can distinguish substrates from inhibitors, unlike radiolabeled and fluorescently-labeled substrate assays.
Sodium-dependent SLC Transporter Assay.
Neurotransmitter Uptake Assay
Contact an ION scientist to discuss how our assay solutions can accelerate your discovery program.
