OG488-HTL

$415.00

OG488-HTL is a photostable, green-fluorescent HaloTag® ligand for any intracellular protein expressing HaloTag® fusion protein. This ligand is extremely pH stable in the physiological range and down to mildly acidic conditions (pKa ~ 4.6), allowing direct covalent labeling. Suitable for localization studies and offering a highly stable complex, easily track the protein of interest and follow its cellular transport.

Variation SKU Price Quantity Action
12.5 µg 4200-HTL $415.00

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SKU: 4200-HTL Category:

Specifications

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Product Description

OG488-HTL is a photostable, green-fluorescent HaloTag® ligand for any intracellular protein expressing HaloTag® fusion protein. This ligand is extremely pH stable in the physiological range and down to mildly acidic conditions (pKa ~ 4.6), allowing direct covalent labeling. Suitable for localization studies and offering a highly stable complex, easily track the protein of interest and follow its cellular transport.

Data

Chemigenetic pH sensors combine precise genetic targeting with interchangeable synthetic fluorophores, enabling selection of the optimal color, photostability, and pKₐ for each application.

OG488-HTL (in green) localized in lysosomes expressing HaloTag®, multiplexed with 6-TMR-HTL (red). Cells were treated with the TMEM175 activator DCPIB and imaged every 30 minutes for 5 hours on a Cytation 5

Documentation

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