$645.00 – $1,495.00
A localizable thallium indicator that can be selectively targeted to individual cells or organelles using HaloTag® technology. ION Thallos Gold-HTL is a ligand for the HaloTag® enzyme, and displays red-shifted excitation and emission relative to ION Thallos-HTL. It can be used to conduct cell-specific potassium channel assays in mixed cell populations, or to probe organellar ion channels in their native environment. Cells expressing HaloTag® are required when using this product.
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Thallos Gold is a gold fluorescent, intracellular thallium (Tl+) indicator. Thallium indicators have been the gold standard for fluorescence-based potassium (K+) channel HTS for nearly 2 decades. ION Thallos Gold-HTL offers the opportunity to localize the indicator to individual cells within a mixed cell population or intracellular compartments using HaloTag® technology, without compromising its Tl+ sensitivity. Once ION Thallos Gold-HTL is loaded into cells expressing HaloTag® protein, the indicator covalently binds to the protein. Addition of stimulus solution will show ion flux within the cell type or intracellular compartment of interest.
Cells expressing HaloTag® are required when using this product.
