Price on request
A recombinant cell line that stably expresses human Kv1.3 (KCNA3) and provides a cell-based model to support discovery and profiling of Kv1.3 inhibitors.
Check out our validated assay formats for this target: Thallium-free GIRK Potassium Channel Assay and Brilliant Thallium Assay (fluorescence-based).
Size: 2 x 10^6M cells
Cells/vial: 2 x 10^6
Mycoplasma test: Pass
Species: Human
Guaranteed performance: > 10 passages
Kv1.3 (KCNA3) is a voltage-gated potassium channel that plays a critical role in the immune system. It regulates T-cell activation by maintaining membrane potential, making it a key target for treating autoimmune diseases. It is also implicated in other conditions, such as cancer and metabolic disorders.
This product is a cell-based, fluorescence-compatible model with stable expression in HEK293T cells, supporting FLIPR, Panoptic and Flexstation workflows in the therapeutic areas noted for this target (Immunology, Cancer, CNS).
