IPG-4 AM

$173.00$391.00

Yellow-green fluorescent, potassium indicator, membrane permeable. Higher potassium affinity than IPG-1 and IPG-2, with improved selectivity for potassium over sodium. 

ION Assurance – We guarantee product quality. If you’re unsatisfied with your order, send us an email at support@ionbiosciences.com. We’ll promptly address your concern and replace, credit, or refund your items according to our ION Assurance terms and conditions.

Frequently bought together

SPECIFICATIONS

Excitation:

525 nm 

Emission:

545 nm 

Kd:

7 mM

MW:

1333

Solubility:

DMSO
Synonyms: Asante Potassium Green, Ion Potassium Green, APG, IPG, APG-4, IPG-4
Product code: 10 x 50ug: 3021F/ 500ug: 3021C

product description

ION Potassium Green – 4 (IPG-4) is a yellow-green fluorescent, potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-selectivity for potassium over other monovalent cations. IPG-4 has the highest affinity (Kd = 7 mM) among IPG analogues – IPG-2 (Kd = 18 mM) and IPG-1 (Kd = 50 mM), and is useful for measuring changes in intracellular or extracellular potassium concentrations.

Click on image to maximize.

IPG-4, a potassium indicator, fluorescence spectra

Click on image to maximize.

GIRK channel (Kir3.1/3.2) activator dose response curve comparison with data acquired using IPG-4 AM on a plate reader and microscope. Inset shows a dose response curve generated using thallium flux.
Fluorescence data of IPG-4 potassium indicator response to potassium.

Click on image to maximize.

Image analysis of IPG-4 assay used to identify activators of a GIRK potassium channel.
Fluorescence profiles and images of cells loaded with IPG-4 in the presence or absence of probenecid demonstrating IPG-4 is not a Pgp substrate, and can be used to conduct probenecid-free potassium channel assays.

Click on image to maximize.

documentation

0