Off-the-shelf cell lines for your drug discovery campaign
Great assays begin with cells that are designed for your end use. That’s why all of our cells have been carefully selected based on functional performance with a pharmacologically relevant, fluorescence-based assay – making them ideally suited for high throughput ion channel and GPCR screening applications.
A human cell line stably expressing a high-conductance GIRK channel for thallium flux assays. Can couple to transiently or stably expressed Gi/o GPCRs for a direct readout of GPCR agonism.
Coming soon!
Coming soon!
Don’t see a cell line expressing your target of interest available, contact us today and our Services team can custom engineer a functional cell line for you.
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| Image | Products | Excitation | Emission | Kd | Price | Quantity | Action |
|---|---|---|---|---|---|---|---|
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Fluo-3 AM Fluo-3 AM is a green fluorescent, calcium indicator. Membrane-permeable. |
$78.00 – $173.00 | |||||
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Brilliant Calcium High-throughput, no wash calcium (Ca²⁺) assay. An optimal solution for measuring intracellular Ca²⁺ dynamics, including effectors such as GPCRs and protein transporters. |
$182.00 – $3,069.00 | |||||
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Brilliant Thallium Gold A potassium channel assay, and so much more. Brilliant Thallium Gold includes Thallos Gold - ION’s gold fluorescent (Ex/Em = 528/552 nm) thallium (Tl+) indicator. Red-shifted excitation and emission enable multiplexing with GFP-expressing cells or other green fluorescent indicators. Useful for fluorescence-based potassium (K+) channel assays and for studying a wide variety of monovalent cation channels (sodium channels), transporters, and GPCRs. |
$211.00 – $473.00 | |||||
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Brilliant Thallium Gold Snapshot Brilliant Thallium Gold Snapshot is a multi-instrument compatible assay solution for well plate-based, high-throughput measurements of thallium flux through potassium, sodium, and non-selective cation channels, as well as some Na+ or K+ transporters. Our patent-pending Snapshot technology generates a long-lasting signal so you can easily detect and quantify changes in ion channel or transporter activity on most fluorescence-capable instruments. The inclusion of Thallos Gold AM, our red-shifted thallium indicator, makes this kit the ideal option when using GFP-expressing cells to run potassium channel assays. |
$211.00 – $473.00 | |||||
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Flow Cytometric Potassium Channel Assay ION Biosciences’ Flow Cytometric Potassium Channel Assay is the first assay solution for single-cell, high-throughput measurements of potassium channel activity. Powered by our patent-pending Snapshot assay technology, ion channel modulation generates a long-lasting signal so you can easily detect and quantify changes in ion channel or transporter activity using Flow Cytometry. This kit may also work for sodium channels, non-selective cation channels, and some Na+ or K+ transporters.200 assays. |
$473.00 | |||||
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Gi/o GPCR-GIRK Thallium Flux Assay A complete Gi/o GPCR assay for discovering modulators through direct coupling to GIRK channels. Cell lines and thallium flux reagents are included. |
$695.00 – $11,690.00 | |||||
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Brilliant Thallium Snapshot An endpoint-compatible potassium channel assay. ION's Brilliant Thallium Snapshot kit is a thallium flux assay adaptation designed to work with standard plate readers, microscopes, flow cytometers, and more, for measuring flux through potassium (K⁺), sodium (Na⁺), and non-selective cation channels, transporters, and their effectors, including GPCRs. |
$211.00 – $473.00 | |||||
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Fluo-Gold AM Fluo-Gold is a gold fluorescent (Ex/Em = 525/550 nm), intracellular calcium indicator. Designed to measure intracellular calcium flux in high throughput screening and fluorescence microscopy applications. Fluo-Gold’s red-shifted excitation and emission enable multiplexing with GFP-expressing cells or other green fluorescent indicators, and minimizes interference from green-fluorescent compounds. |
$88.00 – $198.00 | |||||
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IPG-4 AM Yellow-green fluorescent, potassium indicator, membrane permeable. Higher potassium affinity than IPG-1 and IPG-2, with improved selectivity for potassium over sodium. |
$173.00 – $391.00 | |||||
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Thallos Gold AM Thallos Gold is a gold fluorescent (Ex/Em = 528/552 nm) intracellular thallium (Tl+) indicator. Red-shifted excitation and emission enable multiplexing with GFP-expressing cells or other green fluorescent indicators. Useful for fluorescence-based potassium channel assays and for studying a wide variety of monovalent cation channels (sodium channels), transporters, and GPCRs. |
$242.00 – $545.00 | |||||
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Fura-2 AM UV-excitable, ratiometric green calcium (Ca²⁺) indicator, membrane permeable. |
$110.00 | |||||
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ING-2 TMA⁺ Salt Yellow-green fluorescent sodium indicator, membrane-impermeable. Higher sodium affinity than ING-1. Suitable for high throughput screening of sodium channels and transporters. |
$334.00 | |||||
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ING-2 AM ING-2 AM is a yellow-green fluorescent, sodium indicator. Membrane-permeable. Higher sodium affinity than ING-1. Suitable for high throughput screening of sodium channels and transporters. |
$173.00 – $391.00 | |||||
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Thallos AM Best in class, green fluorescent, thallium (Tl⁺) indicator, membrane permeable. Works with potassium (K⁺), sodium (Na⁺), and monovalent cation channels, and transporters. |
$242.00 – $545.00 | |||||
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Fluo-3 K⁺ Salt Green fluorescent, calcium (Ca²⁺) indicator, membrane impermeable. |
$161.00 | |||||
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Brilliant Thallium A potassium channel assay, and so much more. ION’s high-throughput, no wash thallium (Tl⁺) flux assay is an optimal solution for measuring the activity of potassium (K⁺), sodium (Na⁺), and non-selective cation channels and their effectors including transporters and GPCRs. |
$211.00 – $3,597.00 | |||||
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Brilliant Calcium Gold ION Biosciences Brilliant Calcium Gold Assay is a total assay solution for multi-well plate-based, high-throughput measurements of Ca²⁺ mobilization mediated through a wide-variety of plasma membrane and intracellular calcium channels. The kit includes our Fluo-Gold dye (Ex/Em: 525/550 nm), which is red-shifted for compatibility with GFP and other green fluorescent indicators. |
$182.00 – $399.00 | |||||
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ING-1 AM ING-1 AM is a yellow-green fluorescent, sodium indicator. Membrane-permeable. Lower sodium affinity than ING-2. |
$173.00 – $391.00 | |||||
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ION Essentials Ratiometric Calcium Combines Fura-2 AM with the necessary reagents for conducting no wash, ratiometric calcium flux assays compatible with plate reader and fluorescence microscopy applications. Individual components are provided to give you the flexibility needed to customize your assay. |
$170.00 – $374.00 | |||||
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Fluo-4 AM Ultrapure (>98%) Fluo-4 AM Ultrapure is our highest purity (>98%) grade available. Fluo-4 Ultrapure is the same green fluorescent, calcium indicator you've trusted for decades, with minimal impurities to give you maximum confidence. Membrane-permeable. The most popular solution for high-throughput calcium flux assays and GPCR assays. |
$75.00 – $162.00 |
