Off-the-shelf cell lines for your drug discovery campaign
Great assays begin with cells that are designed for your end use. That’s why all of our cells have been carefully selected based on functional performance with a pharmacologically relevant, fluorescence-based assay – making them ideally suited for high throughput ion channel and GPCR screening applications.
A human cell line stably expressing a high-conductance GIRK channel for thallium flux assays. Can couple to transiently or stably expressed Gi/o GPCRs for a direct readout of GPCR agonism.
A stable CHO cell line overexpressing hERG potassium channels for studying Kv11.1 pharmacology and safety screening.
Coming soon!
A stable, recombinant HEK293T cell line expressing GlyT1 (SLC6A9), validated using glycine uptake assays and suitable for identifying modulators of human GlyT1 activity.
HEK293T GAT1 (SLC6A1) recombinant cell line stably expresses the human GABA transporter and provides a validated in vitro model for studying GAT1 function and pharmacology. This cell line is optimized for high-throughput screening of GAT1 inhibitors or substrates, functional uptake assays, and kinetic studies of transporter activity. Its strong, reproducible sodium-dependent GABA uptake and compatibility with fluorescence-based assays make it an ideal platform for advancing drug discovery efforts targeting GABAergic pathways in CNS disease.
Check out our Sodium-dependent SLC Transporter Assay for a highly-sensitive, robust, and high-throughput method to measure sodium-dependent SLC transporter activity.
Â
Don’t see a cell line expressing your target of interest available, contact us today and our Services team can custom engineer a functional cell line for you.Â
