$475.00 – $997.00
BAPTA JF™549-HTL is a calcium indicator that also displays the Halotag ligand for cell-specific and organellar localization using Halotag technology. A Janelia Fluor® dye backbone provides excellent brightness and photostability, making it useful for measuring fast calcium dynamics in neurons and cardiomyocytes. This calcium indicator also outperforms red-shifted genetically encoded calcium sensors in sensitivity and fluorescence intensity.
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BAPTA JF549-HTL is a red fluorescent (Ex/Em = 546/569 nm), intracellular calcium indicator that displays a chloroalkane ligand for binding to Halotag. The Halotag ligand enables localization to specific cell phenotypes in mixed cell populations and intracellular organelles using Halotag technology. Designed with a Janelia Fluor® dye backbone, the calcium indicator displays excellent brightness and photostability for measuring fast calcium dynamics in neurons and cardiomyocytes. It also outperforms red-shifted genetically encoded calcium sensors in sensitivity and fluorescence intensity. The red-shifted fluorescence minimizes tissue autofluorescence, enables multicolor imaging, and permits the use of optogenetic tools for triggering calcium transients. Halotag expressing cells are required when using this dye.
*JF™ is a trademark owned by the Howard Hughes Medical Institute. Janelia Fluor® is a Registered Trademark of the Howard Hughes Medical Institute.