$334.00
Yellow-green fluorescent sodium indicator, membrane-impermeable. Higher sodium affinity than ING-1. Suitable for high throughput screening of sodium channels and transporters.
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Size: 10 x 50 ug
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2013F
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$334.00
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Size: 500 ug
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2013C
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$334.00
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Excitation: 525 nm
Emission: 545 nm
Kd: 20 mM
MW: 1084 g/mol
Solubility: H2O
Purity: >90%
Filter Set: GFP, FITC, YFP
Storage: -20°C
ION Natrium Green – 2 (ING-2) is a yellow-green fluorescent, intracellular sodium (Na⁺) indicator with improved cellular loading and significantly higher brightness than SBFI. Its spectral properties (Ex/Em: 525 nm/545 nm) and large dynamic range make ING-2 the best Na⁺ indicator for high-throughput screening applications targeting Na⁺ channels, and non-selective monovalent cation channels. ING-2 has a more physiologically relevant affinity (Kd = 20 mM) than ING-1 (Kd = 92 mM). Also compatible with fluorescence microscopy using common fluorescein, GFP or more ideally YFP filters.
ING-2 TMA⁺ salt is a membrane impermeable form of ING-2 that can be used in lipid membrane-free systems, in liposomes, or can be introduced into cells by electroporation, microinjection or other methods.
