ING-2 TMA⁺ Salt

$290.00

Yellow-green fluorescent, sodium (Na⁺) indicator, membrane impermeable. Higher Na⁺ affinity than ING-1

 

Clear

SPECIFICATIONS

Excitation:

525 nm 

Emission:

545 nm 

Kd:

20 mM

MW:

1084

Solubility:

H2O

Synonyms: ION Natrium Green – 2, Asante Natrium Green – 2 (ANG-2)
Product code: 10 x 50ug: 2013F / 500ug: 2013C

product description

ION Natrium Green – 2 (ING-2) is a yellow-green fluorescent, intracellular sodium (Na⁺) indicator with improved cellular loading and significantly higher brightness than SBFI. Its spectral properties (Ex/Em: 525 nm/545 nm) and large dynamic range make ING-2 the best Na⁺ indicator for high-throughput screening applications targeting Na⁺ channels, and non-selective monovalent cation channels. ING-2 has a more physiologically relevant affinity (Kd = 20 mM) than ING-1 (Kd = 92 mM). Also compatible with fluorescence microscopy using common fluorescein, GFP or more ideally YFP filters.

ING-2 TMA⁺ salt is a membrane impermeable form of ING-2 that can be used in lipid membrane-free systems, in liposomes, or can be introduced into cells by electroporation, microinjection or other methods.

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