SPECIFICATIONS
Excitation:
490 nm 
Emission:
515 nm 
MW:
840 g/mol
Product code: 11000-10
product description
ION Biosciences’ Brilliant Thallium (Tl⁺) Assay is a total assay solution for multi-well plate-based, high-throughput measurements of thallium flux through potassium, sodium, non-selective cation channels, and some sodium or potassium transporters. Although thallium is primarily used as a surrogate ion for potassium channel assays, ION’s Brilliant Thallium Assay is also useful for a wide range of effectors of ion channels and transporters including G protein-coupled receptors, and lipid and protein kinases. In multi-well, plate-based formats, the Brilliant Thallium Assay can be used to discover and characterize the effects of tens to many tens-of-thousands of compounds and environmental factors on effectors of thallium flux. Over the past 15 years, fluorescence-based measures of thallium flux have been widely utilized to discover small molecule modulators of a host of ion channels, transporters, GPCRS and other targets of interest for both drug discovery and basic research.
Our Flex kit provides all necessary reagents in a format to maximize flexibility for your assay design and customization challenges.
Potassium and sodium channel assays using thallium flux
documentation
