Brilliant Thallium Flex


A potassium channel assay, and so much more. ION’s high-throughput, no wash thallium (Tl⁺) flux assay is an optimal solution for measuring the activity of potassium (K⁺), sodium (Na⁺), and non-selective cation channels, transporters, and their effectors such as GPCRs. 10 plates

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490 nm 


515 nm 


840 g/mol

Product code: 11000-10

product description

Thallium flux assay banner showing a dose response curve of retigabine activation for the voltage-gated potassium channel, Kv7.2/7.3.

ION Biosciences’ Brilliant Thallium (Tl⁺) Assay is a total assay solution for multi-well plate-based, high-throughput measurements of thallium flux through potassium, sodium, non-selective cation channels, and some sodium or potassium transporters. Although thallium is primarily used as a surrogate ion for potassium channel assays, ION’s Brilliant Thallium Assay is also useful for a wide range of effectors of ion channels and transporters including G protein-coupled receptors, and lipid and protein kinases. In multi-well, plate-based formats, the Brilliant Thallium Assay can be used to discover and characterize the effects of tens to many tens-of-thousands of compounds and environmental factors on effectors of thallium flux. Over the past 15 years, fluorescence-based measures of thallium flux have been widely utilized to discover small molecule modulators of a host of ion channels, transporters, GPCRS and other targets of interest for both drug discovery and basic research.

Our Flex kit provides all necessary reagents in a format to maximize flexibility for your assay design and customization challenges.

Potassium and sodium channel assays using thallium flux