Gi GPCR-GIRK Thallium Flux Assay

Gi GPCR assay, GIRK thallium flux, GPCR agonists, high-throughput screening, dopamine receptors, serotonin receptors, muscarinic receptors, opioid receptors, drug discovery.

Discover ION Biosciences’ Gi/o GPCR-GIRK thallium flux assay for real-time GPCR readouts through a native coupling mechanism to GIRK potassium channels. Unlock high-throughput screening with flexibility to insert any Gi GPCR transiently and uncover new hits. Some validated targets include dopamine, serotonin, muscarinic, and opioid receptors.

Gi GPCR assay, GIRK thallium flux, GPCR agonists, high-throughput screening, dopamine receptors, serotonin receptors, muscarinic receptors, opioid receptors, drug discovery.