Ion Channel
Cell Lines

Ion channel cell lines

Ion channels are essential membrane-bound proteins that control the movement of ions, such as sodium, potassium, calcium, and chloride, across cell membranes and are responsible for the regulation of numerous fundamental physiological processes. In pharmacology, ion channels serve as targets for a wide range of medical conditions, including cardiovascular disorders, neurological conditions, and pain management. Moreover, mutations that affect ion channel activity can lead to channelopathies like long QT syndrome, epilepsy, or cystic fibrosis. ION Biosciences was founded to provide better tools for studying ion channels, such as fluorescent ion indicators, in order to illuminate their roles in cell biology and uncover new modulators for these important membrane proteins. Put our expertise to work and leverage our capabilities to your organization’s benefit.

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Ion Channel Cell Lines

Don’t see a cell line expressing your target of interest available, contact us today and our Services team can custom engineer a functional cell line for you. 

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Image Products Excitation Emission Kd Price Quantity Action
CHO K1 Kv11.1 (hERG) Recombinant cell line
CHO K1 Kv11.1 (hERG) Recombinant cell line
 A stable CHO cell line overexpressing hERG potassium channels for studying Kv11.1 pharmacology and safety screening. Be sure to check out our Brilliant Thallium Assay for a no-wash, high throughput formatted kit, suitable for voltage-gated potassium channels.
$2,700.00
HEK293 Kv11.1 (hERG) Cell Line
HEK293 Kv11.1 (hERG) Cell Line
ION Biosciences’ HEK293 Kv11.1 (hERG) recombinant cell line stably expresses human KCNH2 and provides a robust, well-validated model for investigating Kv11.1 channel function. This cell line is ideally suited for high-throughput screening of channel modulators, safety pharmacology assays, and mechanistic studies aimed at discovering novel inhibitors or activators of Kv11.1. With excellent reproducibility and functional expression, these cells facilitate efficient evaluation of compound effects on Kv11.1 currents using fluorescence-based assays.
Price on request
HEK293 - huKir3.1/3.2 cell line
HEK293 - huKir3.1/3.2 cell line
A stable HEK cell line overexpressing GIRK potassium channels for studying Kir3.1/3.2 pharmacology and Gi/o GPCRs. Be sure to check out our Gi/o GPCR-GIRK Thallium Flux Assay to discover modulators of GIRK potassium channels.
$10,995.00

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