Assay Development Services

From concept to completion — assay development made simple

At ION Biosciences, we specialize in assay development as demonstrated by our history of commercializing proprietary assays for ion channels, transporters, and GPCRs. Our expertise in developing and manufacturing fluorescence-based assay technologies and stable cell lines, combined with advanced instrumentation for even the most complex of protocols, facilitate high-speed, reliable data capture to enable your next discoveries. From start to finish, our team is prepared to deliver the tools you need to achieve your goals. 

What sets us apart is that we manufacture a large collection of fluorescent ion indicators and ready-to-use assay kits for discovering modulators across a broad swath of druggable targets, including ion channels, transporters, and GPCRs. Among these are a suite of proprietary technologies, including:

Sodium channel assay development example that combines a voltage-gated sodium channel expressing cell with Brilliant Sodium 2 for inhibitor screening.

These innovative assays showcase our commitment to advancing drug discovery and developing solutions that provide relevant, actionable insights for your pipeline. All of our assays were developed by the same experts that will support your assay development projects.

Our team is supported by advanced instrumentation that can make even the most challenging of assays, routine. Led by the Panoptic from WaveFront Biosciences, a powerful fluorescence imaging plate reader (FLIPR) that is built on top of an Agilent Bravo liquid handler, that can accommodate 96-384 well plates and fluorescence or luminescence read modes. Panoptic is equipped with:

Look inside our high throughput screening instrument

HTS instrument inside look

We also have a Cytation 5, multimode plate reader and fluorescence imager, and Flexstation III, a lower throughput kinetic plate reader, to meet your assay needs.

Whether you need a specialized high-throughput screening assay developed, stable cell lines expressing your protein or interest, or a fully integrated solution, our team provides expert guidance, competitive pricing, and flexible technology transfer terms to support your next breakthrough. Partner with us to discover a brighter future—contact our experts today.