salt – ION Biosciences

IPG-1 TMA⁺ Salt

adrianpulsodigital — Wed, 28 Jun 2023 19:26:53 +0000

ION Potassium Green – 1 (IPG-1) is the best in class yellow-green fluorescent, intracellular potassium (K⁺) indicator for measuring changes at most intracellular K+ concentrations. IPG-1 has Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. IPG-1 has a lower affinity (Kd = 50 mM) than IPG-2 (Kd = 18 mM) or IPG-4 (Kd = 7 mM)
IPG-1 TMA⁺ salt is a membrane impermeable form of IPG-1 that can be used in lipid membrane-free systems, in liposomes, or can be introduced into cells by electroporation, microinjection or other methods.

SBFI K⁺ Salt

adrianpulsodigital — Wed, 28 Jun 2023 19:26:48 +0000

SBFI is a UV-excitable, ratiometric green indicator for intracellular sodium (Na⁺) measurements. Ex/Em: 340/505 nm can be used to measure Na⁺-bound SBFI, and Ex/Em: 380/505 nm can be used to detect Na⁺-free SBFI. It is ~18X more selective for Na⁺ over K⁺. Ratiometry is optimal for imaging applications where quantification of intracellular Na⁺ concentrations is desired, and reduces effects of photobleaching, heterogenous dye loading, and variable cell morphology.

SBFI K⁺ salt is a membrane impermeable form of SBFI that can be used in lipid membrane-free systems, in liposomes, or can be introduced into cells by electroporation, microinjection or other methods.

Fluo-2 K⁺ Salt

adrianpulsodigital — Wed, 28 Jun 2023 19:26:32 +0000

Fluo-2 is a green fluorescent, calcium (Ca²⁺) indicator. Fluo-2 has higher Ca²⁺ affinity (Kd = 290 nM), superior cell loading and comparable spectral properties compared to Fluo-4. Offers superior sensitivity versus other Fluo analogues at lower Ca²⁺ concentrations.

Fluo-2 K⁺ salt is a membrane impermeable form of Fluo-2 that can be used in lipid membrane-free systems, in liposomes, or can be introduced into cells by electroporation, microinjection or other methods.