ipg2

ipg2-tma

IPG-2 AM

$340.00

Yellow-green fluorescent, potassium (K⁺) indicator, membrane permeable. Lower K⁺ affinity than IPG-4 and higher affinity than IPG-1

SPECIFICATIONS

Excitation:

525 nm

Emission:

545 nm

Kd:

18 mM

MW:

1128

Solubility:

DMSO

Synonyms: Asante Potassium Green, Ion Potassium Green, APG, IPG, APG-2, IPG-2

Product code: 10 x 50ug: 3011F/ 500ug: 3011C

product description

ION Potassium Green – 2 (IPG-2) is a yellow-green fluorescent, intracellular potassium (K⁺) indicator with Ex/Em: 525 nm/545 nm and a high-sensitivity to detect small changes in K⁺ concentration. IPG-2 has a higher affinity (Kd = 18 mM) than IPG-1 (Kd = 50 mM) and lower affinity than IPG-4 (Kd = 7 mM).

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documentation

References

Rana PS, Gibbons BA, Vereninov AA, Yurinskaya VE, Clements RJ, Model TA, Model MA. Calibration and characterization of intracellular Asante Potassium Green probes, APG-2 and APG-4. Anal Biochem. 2019 Feb 15;567:8-13. doi: 10.1016/j.ab.2018.11.024

Liu, J., Li, F., Wang, Y. et al. A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain. Nat. Nanotechnol. 15, 321–330 (2020). https://doi.org/10.1038/s41565-020-0634-4

May LM, Anggono V, Gooch HM, Jang SE, Matusica D, Kerbler GM, Meunier FA, Sah P, Coulson EJ. G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity. Front Neurosci. 2017 Aug 8;11:455. doi: 10.3389/fnins.2017.00455

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