ING-1 AM

$173.00$391.00

ING-1 AM is a yellow-green fluorescent, sodium indicator. Membrane-permeable. Lower sodium affinity than ING-2.

 

Frequently bought together

SPECIFICATIONS

Excitation:

525 nm

Emission:

545 nm

Kd:

92 mM

MW:

1098 g/mol

Solubility:

DMSO

Synonyms: ION Natrium Green – 1, Asante Natrium Green – 1 (ANG-1)
Product code: 10 x 50ug: 2015F / 500mg: 2015C

 

product description

ING-1 (ION natrium green-1) banner describing that it is a low affinity sodium indicator

ION Natrium Green – 2 (ING-2) is a yellow-green fluorescent, intracellular sodium (Na⁺) indicator with improved cellular loading and significantly higher brightness than SBFI. Its spectral properties (Ex/Em: 525 nm/545 nm) and large dynamic range make ING-2 the best Na⁺ indicator for high-throughput screening applications targeting Na⁺ channels, and non-selective monovalent cation channels. ING-2 has a more physiologically relevant affinity (Kd = 20 mM) than ING-1 (Kd = 92 mM). Also compatible with fluorescence microscopy using common fluorescein, GFP or more ideally YFP filters.

excitation and emission spectra of ING-1 (ION natrium green-1), a sodium indicator

Click on image to enlarge.

Fluorescence of ING-1 (ion natrium green-1), a sodium indicator, increases with sodium concentration.

Click on image to enlarge.

Concentration response curve of ouabain, an inhibitor of the sodium/potassium-pump, shows increasing ING-1 fluorescence at higher concentrations

Click on image to enlarge.

documentation

References

0